Inhibition of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Decreases Rat Cortical Neuron Injury and Blood-Brain Barrier Permeability, and Improves Neurological Functional Recovery in Traumatic Brain Injury Model

BACKGROUND AND PURPOSE: Recent evidence has supported the neuroprotective effect of bpV (pic), an inhibitor of phosphatase and tensin homolog deleted on chromosome 10 (PTEN), in models of ischemic stroke. However, whether PTEN inhibitors improve long-term functional recovery after traumatic brain in...

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Hlavní autoři: Ding, Jun, Guo, Jianyi, Yuan, Qiang, Yuan, Fang, Chen, Hao, Tian, Hengli
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842922/
https://ncbi.nlm.nih.gov/pubmed/24312220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080429
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