Inhibition of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Decreases Rat Cortical Neuron Injury and Blood-Brain Barrier Permeability, and Improves Neurological Functional Recovery in Traumatic Brain Injury Model

BACKGROUND AND PURPOSE: Recent evidence has supported the neuroprotective effect of bpV (pic), an inhibitor of phosphatase and tensin homolog deleted on chromosome 10 (PTEN), in models of ischemic stroke. However, whether PTEN inhibitors improve long-term functional recovery after traumatic brain in...

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Detalhes bibliográficos
Main Authors: Ding, Jun, Guo, Jianyi, Yuan, Qiang, Yuan, Fang, Chen, Hao, Tian, Hengli
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842922/
https://ncbi.nlm.nih.gov/pubmed/24312220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080429
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