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VacA, the vacuolating cytotoxin of Helicobacter pylori, binds to multimerin 1 on human platelets

Platelets were activated under the infection with H. pylori in human and mice. We investigated the role of VacA, an exotoxin released by H. pylori in this context. Acid-activated VacA, but not heated VacA, induced platelet CD62P expression. However, VacA reacted with none of the alleged VacA recepto...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Satoh, Kaneo, Hirayama, Toshiya, Takano, Katsuhiro, Suzuki-Inoue, Katsue, Sato, Tadashi, Ohta, Masato, Nakagomi, Junko, Ozaki, Yukio
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842841/
https://ncbi.nlm.nih.gov/pubmed/24219705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-9560-11-23
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