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VacA, the vacuolating cytotoxin of Helicobacter pylori, binds to multimerin 1 on human platelets
Platelets were activated under the infection with H. pylori in human and mice. We investigated the role of VacA, an exotoxin released by H. pylori in this context. Acid-activated VacA, but not heated VacA, induced platelet CD62P expression. However, VacA reacted with none of the alleged VacA recepto...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3842841/ https://ncbi.nlm.nih.gov/pubmed/24219705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-9560-11-23 |
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