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Influenza A penetrates host mucus by cleaving sialic acids with neuraminidase
BACKGROUND: Influenza A virus (IAV) neuraminidase (NA) cleaves sialic acids (Sias) from glycans. Inhibiting NA with oseltamivir suppresses both viral infection, and viral release from cultured human airway epithelial cells. The role of NA in viral exit is well established: it releases budding virion...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3842836/ https://ncbi.nlm.nih.gov/pubmed/24261589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-321 |
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