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Monoclonal antibody-directed effector cells selectively lyse human melanoma cells in vitro and in vivo.

Monoclonal antibody 9.2.27 (mAb 9.2.27) directed to a chondroitin sulfate proteoglycan on human melanoma cells was able to suppress tumor growth in athymic (nu/nu) mice more effectively when bound with polyethylene glycol to murine effector cells than when injected alone. These "armed" effector cell...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Schulz, G, Bumol, T F, Reisfeld, R A
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1983
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384265/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6577434/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.17.5407
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