Monoclonal antibody-directed effector cells selectively lyse human melanoma cells in vitro and in vivo.
Monoclonal antibody 9.2.27 (mAb 9.2.27) directed to a chondroitin sulfate proteoglycan on human melanoma cells was able to suppress tumor growth in athymic (nu/nu) mice more effectively when bound with polyethylene glycol to murine effector cells than when injected alone. These "armed" effector cell...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
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| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
1983
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384265/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6577434/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.17.5407 |
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