Proteomic and Genomic Analyses of Antimony Resistant Leishmania infantum Mutant

BACKGROUND: Antimonials remain the primary antileishmanial drugs in most developing countries. However, drug resistance to these compounds is increasing and our understanding of resistance mechanisms is partial. METHODS/PRINCIPAL FINDINGS: In the present study, quantitative proteomics using stable i...

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Detalhes bibliográficos
Main Authors: Brotherton, Marie-Christine, Bourassa, Sylvie, Leprohon, Philippe, Légaré, Danielle, Poirier, Guy G., Droit, Arnaud, Ouellette, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842243/
https://ncbi.nlm.nih.gov/pubmed/24312377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081899
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