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Oral administration of GZ-793A, a VMAT2 inhibitor, decreases methamphetamine self-administration in rats

Despite the high prevalence of use of methamphetamine (METH), there is no FDA-approved pharmacological treatment available currently for METH addiction. The vesicular monoamine transporter (VMAT2) has been proposed as a novel target to treat METH abuse. GZ-793A, a lobelane analog and selective VMAT2...

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Autors principals: Wilmouth, Carrie E., Zheng, Guangrong, Crooks, Peter A., Dwoskin, Linda P., Bardo, Michael T.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842023/
https://ncbi.nlm.nih.gov/pubmed/24075974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2013.09.006
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