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Effects of VMAT2 inhibitors lobeline and GZ-793A on methamphetamine-induced changes in dopamine release, metabolism and synthesis in vivo

Vesicular monoamine transporter-2 (VMAT2) inhibitors reduce methamphetamine (METH) reward in rats. The current study determined the effects of VMAT2 inhibitors lobeline (LOB; 1 or 3 mg/kg) and N-(1,2R-dihydroxylpropyl)-2,6-cis-di(4-methoxyphenethyl)piperidine hydrochloride (GZ-793A; 15 or 30 mg/kg)...

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Autors principals: Meyer, Andrew C., Neugebauer, Nichole M., Zheng, Guangrong, Crooks, Peter A., Dwoskin, Linda P., Bardo, Michael T.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795981/
https://ncbi.nlm.nih.gov/pubmed/23875705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12373
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