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POLG determines the risk of sodium valproate induced liver toxicity
Sodium valproate (VPA) is widely used throughout the world to treat epilepsy, migraine, chronic headache, bipolar disorder, and as adjuvant chemotherapy. VPA toxicity is an uncommon but potentially fatal cause of idiosyncratic liver injury. Rare mutations in POLG, which codes for the mitochondrial D...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3841971/ https://ncbi.nlm.nih.gov/pubmed/21038416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23891 |
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