Elimination of shelterin components bypasses RNAi for pericentric heterochromatin assembly

The RNAi pathway is required for heterochromatin assembly at repetitive DNA elements in diverse organisms. In fission yeast, loss of RNAi causes pericentric heterochromatin defects, compromising gene silencing and chromosome segregation. Here we show that deletion of telomere shelterin components re...

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Bibliographic Details
Main Authors: Tadeo, Xavier, Wang, Jiyong, Kallgren, Scott P., Liu, Jinqiang, Reddy, Bharat D., Qiao, Feng, Jia, Songtao
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2013
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841737/
https://ncbi.nlm.nih.gov/pubmed/24240238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.226118.113
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