Elimination of shelterin components bypasses RNAi for pericentric heterochromatin assembly

The RNAi pathway is required for heterochromatin assembly at repetitive DNA elements in diverse organisms. In fission yeast, loss of RNAi causes pericentric heterochromatin defects, compromising gene silencing and chromosome segregation. Here we show that deletion of telomere shelterin components re...

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Detalhes bibliográficos
Main Authors: Tadeo, Xavier, Wang, Jiyong, Kallgren, Scott P., Liu, Jinqiang, Reddy, Bharat D., Qiao, Feng, Jia, Songtao
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841737/
https://ncbi.nlm.nih.gov/pubmed/24240238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.226118.113
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