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Elimination of shelterin components bypasses RNAi for pericentric heterochromatin assembly
The RNAi pathway is required for heterochromatin assembly at repetitive DNA elements in diverse organisms. In fission yeast, loss of RNAi causes pericentric heterochromatin defects, compromising gene silencing and chromosome segregation. Here we show that deletion of telomere shelterin components re...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3841737/ https://ncbi.nlm.nih.gov/pubmed/24240238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.226118.113 |
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