Elimination of a specific histone H3K14 acetyltransferase complex bypasses the RNAi pathway to regulate pericentric heterochromatin functions

In Schizosaccharomyces pombe, the RNAi pathway is required for the formation of pericentric heterochromatin, proper chromosome segregation, and repression of pericentric meiotic recombination. Here we demonstrate that, when the activity of the histone H3 Lys 14 (H3K14) acetyltransferase Mst2 is elim...

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Detalhes bibliográficos
Main Authors: Reddy, Bharat D., Wang, Yu, Niu, Lifang, Higuchi, Emily C., Marguerat, Samuel B., Bähler, Jürg, Smith, Gerald R., Jia, Songtao
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034895/
https://ncbi.nlm.nih.gov/pubmed/21289066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1993611
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