Genetically Encoded Immunophotosensitizer 4D5scFv-miniSOG is a Highly Selective Agent for Targeted Photokilling of Tumor Cells In Vitro

Tumor-targeted delivery of cytotoxins presents considerable advantages over their passive transport. Chemical conjugation of cytotoxic module to antibody is limited due to insufficient reproducibility of synthesis, and recombinant immunotoxins are aimed to overcome this disadvantage. We obtained gen...

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Detalhes bibliográficos
Main Authors: Mironova, Kristina E., Proshkina, Galina M., Ryabova, Anastasiya V., Stremovskiy, Oleg A., Lukyanov, Sergey A., Petrov, Rem V., Deyev, Sergey M.
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841334/
https://ncbi.nlm.nih.gov/pubmed/24312153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.6715
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