Genetically Encoded Immunophotosensitizer 4D5scFv-miniSOG is a Highly Selective Agent for Targeted Photokilling of Tumor Cells In Vitro

Tumor-targeted delivery of cytotoxins presents considerable advantages over their passive transport. Chemical conjugation of cytotoxic module to antibody is limited due to insufficient reproducibility of synthesis, and recombinant immunotoxins are aimed to overcome this disadvantage. We obtained gen...

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Main Authors: Mironova, Kristina E., Proshkina, Galina M., Ryabova, Anastasiya V., Stremovskiy, Oleg A., Lukyanov, Sergey A., Petrov, Rem V., Deyev, Sergey M.
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2013
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841334/
https://ncbi.nlm.nih.gov/pubmed/24312153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.6715
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