A transmissible retrovirus expressing human hypoxanthine phosphoribosyltransferase (HPRT): gene transfer into cells obtained from humans deficient in HPRT.

A cDNA corresponding to the human gene for hypoxanthine phosphoribosyltransferase (HPRT; IMP:pyrophosphate phosphoribosyltransferase, EC 2.4.2.8) has been ligated into murine retroviral vectors such that it is under the transcriptional control of viral long terminal repeats. Transfection of HPRT- ce...

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Detalhes bibliográficos
Main Authors: Miller, A D, Jolly, D J, Friedmann, T, Verma, I M
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC384113/
https://ncbi.nlm.nih.gov/pubmed/6308645
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