Methylation status and DNase I sensitivity of immunoglobulin genes: changes associated with rearrangement.
Immunoglobulin V kappa genes are transcriptionally silent in their germline context and become transcriptionally active upon fusion to the J kappa-C kappa region (kappa locus). To elucidate the role of chromosomal structure in this regulatory phenomenon we have investigated the DNase I sensitivity a...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1983
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384109/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6308642/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.15.4689 |
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