Methylation status and DNase I sensitivity of immunoglobulin genes: changes associated with rearrangement.
Immunoglobulin V kappa genes are transcriptionally silent in their germline context and become transcriptionally active upon fusion to the J kappa-C kappa region (kappa locus). To elucidate the role of chromosomal structure in this regulatory phenomenon we have investigated the DNase I sensitivity a...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1983
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384109/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6308642/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.15.4689 |
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