Novel Inhibitors of Rad6 Ubiquitin Conjugating Enzyme: Design, Synthesis, Identification, and Functional Characterization

Lignende værker

• Pharmacological targeting of RAD6 enzyme-mediated translesion synthesis overcomes resistance to platinum-based drugs
  af: Sanders, Matthew A., et al.
  Udgivet: (2017)
• Synthesis and in vitro anticancer evaluation of some 4,6-diamino-1,3,5-triazine-2-carbohydrazides as Rad6 ubiquitin conjugating enzyme inhibitors
  af: Kothayer, Hend, et al.
  Udgivet: (2016)
• Rad6B acts downstream of Wnt signaling to stabilize β-catenin: Implications for a novel Wnt/β-catenin target
  af: Gerard, Brigitte, et al.
  Udgivet: (2011)
• Gold nanoparticle conjugated Rad6 inhibitor induces cell death in triple negative breast cancer cells by inducing mitochondrial dysfunction and PARP-1 hyperactivation: Synthesis and characterization
  af: Haynes, Brittany, et al.
  Udgivet: (2015)
• RAD6B is a major mediator of triple negative breast cancer cisplatin resistance: Regulation of translesion synthesis/Fanconi anemia crosstalk and BRCA1 independence
  af: Haynes, Brittany, et al.
  Udgivet: (2019)