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Role of IGF-1 pathway in lung fibroblast activation
BACKGROUND: IGF-1 is elevated in pulmonary fibrosis and acute lung injury, where fibroblast activation is a prominent feature. We previously demonstrated that blockade of IGF pathway in murine model of lung fibrosis improved outcome and decreased fibrosis. We now expand that study to examine effects...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3840605/ https://ncbi.nlm.nih.gov/pubmed/24103846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-14-102 |
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