Role of integrin alpha8 in murine model of lung fibrosis

BACKGROUND: Integrin α8 (ITGA8) heterodimerizes with integrin β1 and is highly expressed in stromal cells of the lung. Platelet-derived growth factor receptor beta (PDGFRβ+) cells constitute a major population of contractile myofibroblasts in the lung following bleomycin-induced fibrosis. Integrin α...

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Udgivet i:PLoS One
Main Authors: Hung, Chi F., Wilson, Carole L., Chow, Yu-Hua, Schnapp, Lynn M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5973593/
https://ncbi.nlm.nih.gov/pubmed/29813125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197937
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