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A comparison of binding surfaces for SPR biosensing using an antibody-antigen system and affinity distribution analysis

The application of optical biosensors in the study of macromolecular interactions requires immobilization of one binding partner to the surface. It is often highly desirable that the immobilization is uniform and does not affect the thermodynamic and kinetic binding parameters to soluble ligands. To...

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Hlavní autoři: Zhao, Huaying, Gorshkova, Inna I., Fu, Gregory L., Schuck, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840496/
https://ncbi.nlm.nih.gov/pubmed/23270815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2012.12.007
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