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Bayesian Analysis of Heterogeneity in the Distribution of Binding Properties of Immobilized Surface Sites

Once a homogeneous ensemble of a protein ligand is taken from solution and immobilized to a surface, for many reasons the resulting ensemble of surface binding sites may be heterogeneous. For example, this can be due to the intrinsic surface roughness causing variations in the local microenvironment...

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Detalhes bibliográficos
Main Authors: Gorshkova, Inna I., Svitel, Juraj, Razjouyan, Faezeh, Schuck, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574969/
https://ncbi.nlm.nih.gov/pubmed/18816013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/la801186w
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