Combined Affinity and Rate Constant Distributions of Ligand Populations from Experimental Surface Binding Kinetics and Equilibria

The present article considers the influence of heterogeneity in a mobile analyte or in an immobilized ligand population on the surface binding kinetics and equilibrium isotherms. We describe strategies for solving the inverse problem of calculating two-dimensional distributions of rate and affinity...

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Hlavní autoři: Svitel, Juraj, Balbo, Andrea, Mariuzza, Roy A., Gonzales, Noreen R., Schuck, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2003
Témata:
Spectroscopy, Imaging, Other Techniques
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302986/
https://ncbi.nlm.nih.gov/pubmed/12770910
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