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Simultaneous Measurement of 10,000 Protein-Ligand Affinity Constants Using Microarray-Based Kinetic Constant Assays

Fluorescence-based endpoint detection of microarrays with 10,000 or more molecular targets is a most useful tool for high-throughput profiling of biomolecular interactions, including screening large molecular libraries for novel protein ligands. However, endpoint fluorescence data such as images of...

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Detalhes bibliográficos
Main Authors: Landry, James P., Fei, Yiyan, Zhu, Xiangdong
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374384/
https://ncbi.nlm.nih.gov/pubmed/22192305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2011.0406
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