Sedimentation Velocity Analysis of Heterogeneous Protein-Protein Interactions: Lamm Equation Modeling and Sedimentation Coefficient Distributions c(s)

We describe algorithms for solving the Lamm equations for the reaction-diffusion-sedimentation process in analytical ultracentrifugation, and examine the potential and limitations for fitting experimental data. The theoretical limiting case of a small, uniformly distributed ligand rapidly reacting w...

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Hlavní autoři: Dam, Julie, Velikovsky, Carlos A., Mariuzza, Roy A., Urbanke, Claus, Schuck, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2005
Témata:
Spectroscopy, Imaging, Other Techniques
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366561/
https://ncbi.nlm.nih.gov/pubmed/15863475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.059568
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