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Effective gene therapy for haemophilic mice with pathogenic factor IX antibodies
Formation of pathogenic antibodies is a major problem in replacement therapies for inherited protein deficiencies. For example, antibodies to coagulation factors (‘inhibitors’) seriously complicate treatment of haemophilia. While immune tolerance induction (ITI) protocols have been developed, inhibi...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Blackwell Publishing Ltd
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3840486/ https://ncbi.nlm.nih.gov/pubmed/24106230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201302859 |
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