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Hepatic Gene Transfer as a Means of Tolerance Induction to Transgene Products

The liver is a preferred target organ for gene therapy not only for liver-specific diseases but also for disorders that require systemic delivery of a protein. Diseases that could benefit from hepatic gene transfer include hemophilia, metabolic disorders, lysosomal storage disorders, and others. For...

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Autori principali: LoDuca, Paul A., Hoffman, Brad E., Herzog, Roland W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851180/
https://ncbi.nlm.nih.gov/pubmed/19355868
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