Shivering and tachycardic responses to external cooling in mice are substantially suppressed by TRPV1 activation but not by TRPM8 inhibition

Mild decrease of core temperature (32–34°C), also known as therapeutic hypothermia, is a highly effective strategy of neuroprotection from ischemia and holds significant promise in the treatment of stroke. However, induction of hypothermia in conscious stroke patients is complicated by cold-defensiv...

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Detalhes bibliográficos
Main Authors: Feketa, Viktor V., Balasubramanian, Adithya, Flores, Christopher M., Player, Mark R., Marrelli, Sean P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Neural Control
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840321/
https://ncbi.nlm.nih.gov/pubmed/24005250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00296.2013
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