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Pharmacologically induced hypothermia via TRPV1 channel agonism provides neuroprotection following ischemic stroke when initiated 90 min after reperfusion

Traditional methods of therapeutic hypothermia show promise for neuroprotection against cerebral ischemia-reperfusion (I/R), however, with limitations. We examined effectiveness and specificity of pharmacological hypothermia (PH) by transient receptor potential vanilloid 1 (TRPV1) channel agonism in...

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Detalhes bibliográficos
Main Authors: Cao, Zhijuan, Balasubramanian, Adithya, Marrelli, Sean P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921315/
https://ncbi.nlm.nih.gov/pubmed/24305062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00329.2013
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