Differential autophagy power in the spinal cord and muscle of transgenic ALS mice

Amyotrophic lateral sclerosis (ALS) is a motoneuron disease characterized by misfolded proteins aggregation in affected motoneurons. In mutant SOD1 (mutSOD1) ALS models, aggregation correlates to impaired functions of proteasome and/or autophagy, both essential for the intracellular chaperone-mediat...

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Detalhes bibliográficos
Main Authors: Crippa, Valeria, Boncoraglio, Alessandra, Galbiati, Mariarita, Aggarwal, Tanya, Rusmini, Paola, Giorgetti, Elisa, Cristofani, Riccardo, Carra, Serena, Pennuto, Maria, Poletti, Angelo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840302/
https://ncbi.nlm.nih.gov/pubmed/24324403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00234
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