COX-1-derived PGE(2) and PGE(2) type 1 receptors are vital for angiotensin II-induced formation of reactive oxygen species and Ca(2+) influx in the subfornical organ

Regulation of blood pressure by angiotensin II (ANG II) is a process that involves the reactive oxygen species (ROS) and calcium. We have shown that ANG-II type 1 receptor (AT(1)R) and prostaglandin E(2) (PGE(2)) type 1 receptors (EP(1)R) are required in the subfornical organ (SFO) for ROS-mediated...

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Main Authors: Wang, Gang, Sarkar, Pallabi, Peterson, Jeffrey R., Anrather, Josef, Pierce, Joseph P., Moore, Jamie M., Feng, Ji, Zhou, Ping, Milner, Teresa A., Pickel, Virginia M., Iadecola, Costantino, Davisson, Robin L.
格式: Artigo
語言:Inglês
出版: American Physiological Society 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840259/
https://ncbi.nlm.nih.gov/pubmed/24014678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00238.2013
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