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Endothelin 1–Dependent Neurovascular Dysfunction in Chronic Intermittent Hypoxia

Obstructive sleep apnea, a condition resulting in chronic intermittent hypoxia (CIH), is an independent risk factor for stroke and dementia, but the mechanisms of the effect are unknown. We tested the hypothesis that CIH increases cerebrovascular risk by altering critical mechanisms regulating cereb...

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Detalhes bibliográficos
Main Authors: Capone, Carmen, Faraco, Giuseppe, Coleman, Christal, Young, Colin N., Pickel, Virginia M., Anrather, Josef, Davisson, Robin L., Iadecola, Costantino
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529143/
https://ncbi.nlm.nih.gov/pubmed/22689747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.112.193672
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