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Circulating endothelin-1 alters critical mechanisms regulating the cerebral microcirculation

Endothelin-1 (ET1) is a potent vasoconstrictor peptide implicated in the cerebrovascular alterations occurring in stroke, subarachnoid hemorrhage, and brain trauma. Brain and/or circulating levels of ET1 are elevated in these conditions and in risk factors for cerebrovascular diseases. Most studies...

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Detalhes bibliográficos
Main Authors: Faraco, Giuseppe, Moraga, Ana, Moore, Jamie, Anrather, Joseph, Pickel, Virginia M., Iadecola, Costantino
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874144/
https://ncbi.nlm.nih.gov/pubmed/23959559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.113.01761
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