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Amino acid mutations in the caldesmon COOH-terminal functional domain increase force generation in bladder smooth muscle

Caldesmon (CaD), a component of smooth muscle thin filaments, binds actin, tropomyosin, calmodulin, and myosin and inhibits actin-activated ATP hydrolysis by smooth muscle myosin. Internal deletions of the chicken CaD functional domain that spans from amino acids (aa) 718 to 731, which corresponds t...

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Bibliografische gegevens
Hoofdauteurs: Deng, Maoxian, Boopathi, Ettickan, Hypolite, Joseph A., Raabe, Tobias, Chang, Shaohua, Zderic, Stephen, Wein, Alan J., Chacko, Samuel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840250/
https://ncbi.nlm.nih.gov/pubmed/23986516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00174.2013
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