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GATA-6 and NF-κB Activate CPI-17 Gene Transcription and Regulate Ca(2+) Sensitization of Smooth Muscle Contraction

Protein kinase C (PKC)-potentiated inhibitory protein of 17 kDa (CPI-17) inhibits myosin light chain phosphatase, altering the levels of myosin light chain phosphorylation and Ca(2+) sensitivity in smooth muscle. In this study, we characterized the CPI-17 promoter and identified binding sites for GA...

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Detalhes bibliográficos
Main Authors: Boopathi, Ettickan, Hypolite, Joseph A., Zderic, Stephen A., Gomes, Cristiano Mendes, Malkowicz, Bruce, Liou, Hsiou-Chi, Wein, Alan J., Chacko, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623078/
https://ncbi.nlm.nih.gov/pubmed/23275439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00626-12
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