Transcriptional Repression of Caveolin-1 (CAV1) Gene Expression by GATA-6 in Bladder Smooth Muscle Hypertrophy in Mice and Human Beings

Hypertrophy occurs in urinary bladder wall smooth muscle (BSM) in men with partial bladder outlet obstruction (PBOO) caused by benign prostatic hyperplasia (BPH) and in animal models of PBOO. Hypertrophied BSM from the rabbit model exhibits down-regulation of caveolin-1, a structural and functional...

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Main Authors: Boopathi, Ettickan, Gomes, Cristiano Mendes, Goldfarb, Robert, John, Mary, Srinivasan, Vittala Gopal, Alanzi, Jaber, Malkowicz, S. Bruce, Kathuria, Hasmeena, Zderic, Stephen A., Wein, Alan J., Chacko, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081182/
https://ncbi.nlm.nih.gov/pubmed/21514437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.01.038
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