Reduced colonic microbial diversity is associated with colitis in NHE3-deficient mice

Chronic inflammation and enteric infections are frequently associated with epithelial Na(+)/H(+) exchange (NHE) inhibition. Alterations in electrolyte transport and in mucosal pH associated with inflammation may represent a key mechanism leading to changes in the intestinal microbial composition. NH...

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Bibliografiska uppgifter
Huvudupphovsmän: Larmonier, Claire B., Laubitz, Daniel, Hill, Faihza M., Shehab, Kareem W., Lipinski, Leszek, Midura-Kiela, Monica T., McFadden, Rita-Marie T., Ramalingam, Rajalakshmy, Hassan, Kareem A., Golebiewski, Marcin, Besselsen, David G., Ghishan, Fayez K., Kiela, Pawel R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2013
Ämnen:
Inflammation/Immunity/Mediators
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840234/
https://ncbi.nlm.nih.gov/pubmed/24029465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00189.2013
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