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NHE3 modulates the severity of colitis in IL-10-deficient mice
NHE3, the major intestinal Na(+)/H(+) exchanger, was shown to be downregulated and/or inhibited in patients with inflammatory bowel disease (IBD), a phenomenon believed to contribute to inflammation-associated diarrhea. NHE3(−/−) mice spontaneously develop colitis and demonstrate high susceptibility...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3119112/ https://ncbi.nlm.nih.gov/pubmed/21415416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00073.2011 |
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