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Punicalagin, a polyphenol in pomegranate juice, downregulates p53 and attenuates hypoxia-induced apoptosis in cultured human placental syncytiotrophoblasts

Oxidative stress is associated with placental dysfunction and suboptimal pregnancy outcomes. Therapeutic interventions to limit placental injury from oxidative stress are lacking. Punicalagin is an ellagitannin and a potent antioxidant in pomegranate juice. We showed that both pomegranate juice and...

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Bibliografiske detaljer
Main Authors: Chen, Baosheng, Longtine, Mark S., Nelson, D. Michael
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840214/
https://ncbi.nlm.nih.gov/pubmed/24085032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00218.2013
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