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Punicalagin, a polyphenol in pomegranate juice, downregulates p53 and attenuates hypoxia-induced apoptosis in cultured human placental syncytiotrophoblasts

Oxidative stress is associated with placental dysfunction and suboptimal pregnancy outcomes. Therapeutic interventions to limit placental injury from oxidative stress are lacking. Punicalagin is an ellagitannin and a potent antioxidant in pomegranate juice. We showed that both pomegranate juice and...

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書目詳細資料
Main Authors: Chen, Baosheng, Longtine, Mark S., Nelson, D. Michael
格式: Artigo
語言:Inglês
出版: American Physiological Society 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840214/
https://ncbi.nlm.nih.gov/pubmed/24085032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00218.2013
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