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Punicalagin, a polyphenol in pomegranate juice, downregulates p53 and attenuates hypoxia-induced apoptosis in cultured human placental syncytiotrophoblasts

Oxidative stress is associated with placental dysfunction and suboptimal pregnancy outcomes. Therapeutic interventions to limit placental injury from oxidative stress are lacking. Punicalagin is an ellagitannin and a potent antioxidant in pomegranate juice. We showed that both pomegranate juice and...

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Detalhes bibliográficos
Main Authors: Chen, Baosheng, Longtine, Mark S., Nelson, D. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840214/
https://ncbi.nlm.nih.gov/pubmed/24085032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00218.2013
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