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Punicalagin, a polyphenol in pomegranate juice, downregulates p53 and attenuates hypoxia-induced apoptosis in cultured human placental syncytiotrophoblasts

Oxidative stress is associated with placental dysfunction and suboptimal pregnancy outcomes. Therapeutic interventions to limit placental injury from oxidative stress are lacking. Punicalagin is an ellagitannin and a potent antioxidant in pomegranate juice. We showed that both pomegranate juice and...

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Bibliografiska uppgifter
Huvudupphovsmän: Chen, Baosheng, Longtine, Mark S., Nelson, D. Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840214/
https://ncbi.nlm.nih.gov/pubmed/24085032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00218.2013
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