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Long-gradient separations coupled with selected reaction monitoring for highly sensitive, large scale targeted protein quantification in a single analysis

Long-gradient separations coupled to tandem MS were recently demonstrated to provide a deep proteome coverage for global proteomics; however, such long-gradient separations have not been explored for targeted proteomics. Herein, we investigate the potential performance of the long-gradient separatio...

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Hlavní autoři: Shi, Tujin, Fillmore, Thomas L., Gao, Yuqian, Zhao, Rui, He, Jintang, Schepmoes, Athena A., Nicora, Carrie D., Wu, Chaochao, Chambers, Justin L., Moore, Ronald J., Kagan, Jacob, Srivastava, Sudhir, Liu, Alvin Y., Rodland, Karin D., Liu, Tao, Camp, David G., Smith, Richard D., Qian, Wei-Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839867/
https://ncbi.nlm.nih.gov/pubmed/24004026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac402105s
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