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Detection and mapping of 5-methylcytosine and 5-hydroxymethylcytosine with nanopore MspA
Precise and efficient mapping of epigenetic markers on DNA may become an important clinical tool for prediction and identification of ailments. Methylated CpG sites are involved in gene expression and are biomarkers for diseases such as cancer. Here, we use the engineered biological protein pore Myc...
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| Päätekijät: | , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839702/ https://ncbi.nlm.nih.gov/pubmed/24167255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310240110 |
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