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MspA nanopore as a single-molecule tool: From sequencing to SPRNT

Single-molecule picometer resolution nanopore tweezers (SPRNT) is a new tool for analyzing the motion of nucleic acids through molecular motors. With SPRNT, individual enzymatic motions along DNA as small as 40 pm can be resolved on sub-millisecond time scales. Additionally, SPRNT reveals an enzyme’...

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Detalles Bibliográficos
Publicado en:Methods
Main Authors: Laszlo, Andrew H., Derrington, Ian M., Gundlach, Jens H.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967004/
https://ncbi.nlm.nih.gov/pubmed/27045943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2016.03.026
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