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Nucleotide Discrimination with DNA Immobilized in the MspA Nanopore

Nanopore sequencing has the potential to become a fast and low-cost DNA sequencing platform. An ionic current passing through a small pore would directly map the sequence of single stranded DNA (ssDNA) driven through the constriction. The pore protein, MspA, derived from Mycobacterium smegmatis, has...

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Main Authors: Manrao, Elizabeth A., Derrington, Ian M., Pavlenok, Mikhail, Niederweis, Michael, Gundlach, Jens H.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186796/
https://ncbi.nlm.nih.gov/pubmed/21991340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025723
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