Llwytho...

Molecular Dynamics Study of MspA Arginine-Mutants Predicts Slow DNA Translocations and Ion Current Blockades Indicative of DNA Sequence

The protein nanopore Mycobacteria smegmatis porin A (MspA), can be used to sense individual nucleotides within DNA, potentially enabling a technique known as nanopore sequencing. In this technique, single stranded DNA electrophoretically moves through the nanopore and results in an ionic current tha...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bhattacharya, Swati, Derrington, Ian M., Pavlenok, Mikhail, Niederweis, Michael, Gundlach, Jens H., Aksimentiev, Aleksei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448955/
https://ncbi.nlm.nih.gov/pubmed/22747101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn3019943
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