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Molecular Dynamics Study of MspA Arginine-Mutants Predicts Slow DNA Translocations and Ion Current Blockades Indicative of DNA Sequence
The protein nanopore Mycobacteria smegmatis porin A (MspA), can be used to sense individual nucleotides within DNA, potentially enabling a technique known as nanopore sequencing. In this technique, single stranded DNA electrophoretically moves through the nanopore and results in an ionic current tha...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3448955/ https://ncbi.nlm.nih.gov/pubmed/22747101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn3019943 |
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