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TAp73 knockout mice show morphological and functional nervous system defects associated with loss of p75 neurotrophin receptor
Total and N-terminal isoform selective p73 knockout mice show a variety of central nervous system defects. Here we show that TAp73 is a transcriptional activator of p75 neurotrophin receptor (p75(NTR)) and that p75(NTR) mRNA and protein levels are strongly reduced in the central and peripheral nervo...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839698/ https://ncbi.nlm.nih.gov/pubmed/24190996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221172110 |
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