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Molecular Mechanisms of SH2- and PTB-Domain-Containing Proteins in Receptor Tyrosine Kinase Signaling

Intracellular signaling is mediated by reversible posttranslational modifications (PTMs) that include phosphorylation, ubiquitination, and acetylation, among others. In response to extracellular stimuli such as growth factors, receptor tyrosine kinases (RTKs) typically dimerize and initiate signalin...

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書誌詳細
主要な著者: Wagner, Melany J., Stacey, Melissa M., Liu, Bernard A., Pawson, Tony
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839611/
https://ncbi.nlm.nih.gov/pubmed/24296166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a008987
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