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Multidrug resistance in chronic myeloid leukaemia: how much can we learn from MDR–CML cell lines?
The hallmark of CML (chronic myeloid leukaemia) is the BCR (breakpoint cluster region)–ABL fusion gene. CML evolves through three phases, based on both clinical and pathological features: a chronic phase, an accelerated phase and blast crisis. TKI (tyrosine kinase inhibitors) are the treatment modal...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Portland Press Ltd.
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839595/ https://ncbi.nlm.nih.gov/pubmed/24070327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20130067 |
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