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Genome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in Kenya

Early identification of causal genetic variants underlying antimalarial drug resistance could provide robust epidemiological tools for timely public health interventions. Using a novel natural genetics strategy for mapping novel candidate genes we analyzed >75,000 high quality single nucleotide p...

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Bibliografiske detaljer
Main Authors: Borrmann, Steffen, Straimer, Judith, Mwai, Leah, Abdi, Abdirahman, Rippert, Anja, Okombo, John, Muriithi, Steven, Sasi, Philip, Kortok, Moses Mosobo, Lowe, Brett, Campino, Susana, Assefa, Samuel, Auburn, Sarah, Manske, Magnus, Maslen, Gareth, Peshu, Norbert, Kwiatkowski, Dominic P., Marsh, Kevin, Nzila, Alexis, Clark, Taane G.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839035/
https://ncbi.nlm.nih.gov/pubmed/24270944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03318
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