Genome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in Kenya

Early identification of causal genetic variants underlying antimalarial drug resistance could provide robust epidemiological tools for timely public health interventions. Using a novel natural genetics strategy for mapping novel candidate genes we analyzed >75,000 high quality single nucleotide p...

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Autors principals: Borrmann, Steffen, Straimer, Judith, Mwai, Leah, Abdi, Abdirahman, Rippert, Anja, Okombo, John, Muriithi, Steven, Sasi, Philip, Kortok, Moses Mosobo, Lowe, Brett, Campino, Susana, Assefa, Samuel, Auburn, Sarah, Manske, Magnus, Maslen, Gareth, Peshu, Norbert, Kwiatkowski, Dominic P., Marsh, Kevin, Nzila, Alexis, Clark, Taane G.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839035/
https://ncbi.nlm.nih.gov/pubmed/24270944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03318
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