Lanean...

Subtle changes to polymer structure and degradation mechanism enable highly effective nanoparticles for siRNA and DNA delivery to human brain cancer

Polymeric materials can be used to deliver nucleic acids such as DNA plasmids and siRNA, but often have low efficacy in human cells. To improve gene delivery, we synthesized an array of over 70 hydrolytically degradable and bioreducible poly(beta-amino ester)s and evaluated properties of over 200 na...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tzeng, Stephany Y., Green, Jordan J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838886/
https://ncbi.nlm.nih.gov/pubmed/23184674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201200257
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